Genetics and Genomics of Social Behavior in a Chicken Model

Sammanfattning

The identification of genes affecting sociality can give insights into the maintenance and development of sociality and personality. In this study, we used the combination of an advanced intercross between wild and domestic chickens with a combined QTL and eQTL genetical genomics approach to identify genes for social reinstatement, a social and anxiety-related behavior. A total of 24 social reinstatement QTL were identified and overlaid with over 600 eQTL obtained from the same birds using hypothalamic tissue. Correlations between overlapping QTL and eQTL indicated 5 strong candidate genes, with the gene TTRAP being strongly significantly correlated with multiple aspects of social reinstatement behavior, as well as possessing a highly significant eQTL.

Nyckelord

behavior; eQTL; QTL; sociality

Publicerad i

Genetics
2018, volym: 209, nummer: 1, sidor: 209-221
Utgivare: Genetics

SLU författare

• Johnsson, Martin

  • Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
    
  • Linköpings universitet
  • University of Edinburgh

• Jensen, Per

  • Linköpings universitet

UKÄ forskningsämne

Genetik

Publikationens identifierare

• DOI: https://doi.org/10.1534/genetics.118.300810

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/94335