Evolutionary dynamics and adaptive benefits of deleterious mutations in crop gene pools

Sammanfattning

Mutations with deleterious consequences in nature may be conditionally deleterious in crop plants. That is, while some genetic variants may reduce fitness under wild conditions and be subject to purifying selection, they can be under positive selection in domesticates. Such deleterious alleles can be plant breeding targets, particularly for complex traits. The difficulty of distinguishing favorable from unfavorable variants reduces the power of selection, while favorable trait variation and heterosis may be attributable to deleterious alleles. Here, we review the roles of deleterious mutations in crop breeding and discuss how they can be used as a new avenue for crop improvement with emerging genomic tools, including HapMaps and pangenome analysis, aiding the identification, removal, or exploitation of deleterious mutations.

Nyckelord

crop improvement; deleterious variants; genome editing; genomic prediction; HapMaps; mating system; propagation; selective sweeps; wild relatives

Publicerad i

Trends in Plant Science
2023, volym: 28, nummer: 6, sidor: 685-697

SLU författare

• Ortiz Rios, Rodomiro Octavio

  • Institutionen för växtförädling, Sveriges lantbruksuniversitet
    

Globala målen (SDG)

SDG2 Ingen hunger

UKÄ forskningsämne

Genetik och förädling inom lantbruksvetenskap
Växtbioteknologi
Jordbruksvetenskap

Publikationens identifierare

• DOI: https://doi.org/10.1016/j.tplants.2023.01.006

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/121216