Niarchos, Georgios
- Institutionen för vatten och miljö, Sveriges lantbruksuniversitet
Översiktsartikel2024Vetenskapligt granskadÖppen tillgång
Niarchos, Georgios; Alygizakis, Nikiforos; Carere, Mario; Dulio, Valeria; Engwall, Magnus; Hyotylainen, Tuulia; Kallenborn, Roland; Karakitsios, Spyros; Karakoltzidis, Achilleas; Karrman, Anna; Lamoree, Marja; Larsson, Maria; Lundqvist, Johan; Mancini, Laura; Mottaghipisheh, Javad; Rostkowski, Pawel; Sarigiannis, Dimosthenis; Vorkamp, Katrin; Ahrens, Lutz
Existing regulatory frameworks often prove inadequate in identifying contaminants of emerging concern (CECs) and determining their impacts on biological systems at an early stage. The establishment of Early Warning Systems (EWSs) for CECs is becoming increasingly relevant for policy-making, aiming to proactively detect chemical hazards and implement effective mitigation measures. Effect-based methodologies, including bioassays and effect-directed analysis (EDA), offer valuable input to EWSs with a view to pinpointing the relevant toxicity drivers and prioritizing the associated risks. This review evaluates the analytical techniques currently available to assess biological effects, and provides a structured plan for their systematic integration into an EWS for hazardous chemicals in the environment. Key scientific advancements in effect-based approaches and EDA are discussed, underscoring their potential for early detection and management of chemical hazards. Additionally, critical challenges such as data integration and regulatory alignment are addressed, emphasizing the need for continuous improvement of the EWS and the incorporation of analytical advancements to safeguard environmental and public health from emerging chemical threats.
Contaminants of emerging concern; Bioassays; Effect-based methods; Effect-directed analysis; Environmental monitoring; Toxicity
Trends in Analytical Chemistry
2024, Volym: 180, artikelnummer: 117901Utgivare: ELSEVIER SCI LTD
Miljövetenskap
Analytisk kemi
DOI: https://doi.org/10.1016/j.trac.2024.117901
https://res.slu.se/id/publ/131991