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Konferensartikel2022Vetenskapligt granskadÖppen tillgång

The effect of recombination rate on genomic selection in simulation

Johnsson, Martin; Johansson, Anna Maria; Klingström, Tomas; Rius-Vilarrasa, E.

Sammanfattning

Genome features such as recombination rate vary between different regions of the genome and affect the distribution of genetic variation, thus potentially affecting the response of the genome to selection and the accuracy of genomic selection. In this paper, we build a quantitative genetic simulation with variable recombination rate based on real linkage maps. It confirms that higher recombination rate causes a somewhat higher long-term genetic gain due to preservation of additive genetic variance, and that high recombination rate lowers the accuracy of genomic selection. While the benefit happens in the long term, the decreased accuracy is immediate.

Publicerad i

Titel: Proceedings of 12th World Congress on Genetics Applied to Livestock Production (WCGALP) : Technical and species orientated innovations in animal breeding, and contribution of genetics to solving societal challenges
eISBN: 978-90-8686-940-4Utgivare: Wageningen Academic Publishers

Konferens

12th World Congress on Genetics Applied to Livestock Production (WCGALP). 2022-07-03, Wageningen, the Netherlands