Kenne, Lennart
- Department of Molecular Sciences, Swedish University of Agricultural Sciences
Abstract
The interaction between (-)-epigallocatechin-'3-gallate (EGCG) and beta- or gamma-cyclodextrin (CD), in free solution and bonded to silica beads, has been studied by H-1 HR-MAS NMR spectroscopy. The chromatographic retardation of EGCG on columns packed with CD-silica beads was shown to be due to the interaction of EGCG with the CD ligands because no nonspecific interaction with the silica gel could be observed. EGCG forms a tighter complex with beta-CD than with gamma-CD and NMR data obtained from hydroxy protons together with mm2 calculations suggest that for beta-CD intermolecular hydrogen bonding, in addition to hydrophobic interaction, stabilizes the complex. (c) 2007 Elsevier Ltd. All rights reserved
Published in
Carbohydrate Research
2007, volume: 342, number: 6, pages: 843-850
Publisher: ELSEVIER SCI LTD
SLU Authors
Sandström, Corine
- Department of Molecular Sciences, Swedish University of Agricultural Sciences
- Department of Molecular Sciences, Swedish University of Agricultural Sciences
Publication identifier
- DOI: https://doi.org/10.1016/j.carres.2007.01.007
Permanent link to this page (URI)
https://res.slu.se/id/publ/14074