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Forskningsartikel2007Vetenskapligt granskad

Quantitative structure-activity relationships of pine weevil antifeedants, a Multivariate approach

Sunnerheim K, Nordqvist A, Nordlander G, Borg-Karlson AK, Unelius CR, Bohman B, Nordenhem H, Hellqvist C, Karlen A

Sammanfattning

Antifeedant activity of mainly phenylpropanoic, cinnamic, and benzoic acids esters was tested on the pine weevil, Hylobius abiefis (L.). Of 105 compounds screened for activity, 9 phenylpropanoates, 3 cinnamates, and 4 benzoates were found to be highly active antifeeclants. To understand the structure-activity relationships of these compounds, a multivariate analysis study was performed. A number of molecular and substituent descriptors were calculated and correlated to results from two-choice feeding tests with H. abietis. Three local models were developed that had good internal predictive ability. External test sets showed moderate predictivity. In general, low polarity, small size, and high lipophilicity were characteristics for compounds having good antifeeclant activity

Publicerad i

Journal of Agricultural and Food Chemistry
2007, Volym: 55, nummer: 23, sidor: 9365-9372
Utgivare: AMER CHEMICAL SOC

      SLU författare

      • Nordenhem, Henrik

        • Institutionen för entomologi, Sveriges lantbruksuniversitet
      • UKÄ forskningsämne

        Skogsvetenskap
        Miljö- och naturvårdsvetenskap

        Publikationens identifierare

        DOI: https://doi.org/10.1021/ifO70014p

        Permanent länk till denna sida (URI)

        https://res.slu.se/id/publ/15455