Abstract

This article describes a multifrequency electrochemical impedance study of phospholipid monolayers on a mercury drop electrode in solutions containing electrolytes and gramicidin derivatives: gramicidin A (gA), gramicidin-BOC (g-BOC), and desformylgramicidin (g-des). The impedance spectra have been studied individually (univariate approach) and also transformed using a multivariate data reduction method (multivariate approach). It was shown that the two approaches are complementary. Thus the formation of K+-conducting channels is observed in gA only, and these channels can be distinguished from an interaction of all gramicidin derivatives with Mg2+. An unknown peptide interaction in the monolayer was observed on a slow time scale

Published in

Langmuir
2007, Volume: 23, number: 9, pages: 5029-5032
Publisher: AMER CHEMICAL SOC

SLU Authors

• Geladi, Paul

  • Department of Forest Biomaterials and Technology, Swedish University of Agricultural Sciences
    

Publication identifier

DOI: https://doi.org/10.1021/la062850j

Permanent link to this page (URI)

https://res.slu.se/id/publ/17279