Support of Concept That Migrating Progenitor Cells From Stem Cell Niches Contribute to Normal Regeneration of the Adult Mammal Intervertebral Disc A Descriptive Study in the New Zealand White Rabbit

Henriksson, Helena Barreto; Svala, Emilia; Skiöldebrand, Eva; Lindahl, Anders; Brisby, Helena

doi:10.1097/BRS.0b013e318231c2f7

Forskningsartikel2012Vetenskapligt granskad

Support of Concept That Migrating Progenitor Cells From Stem Cell Niches Contribute to Normal Regeneration of the Adult Mammal Intervertebral Disc A Descriptive Study in the New Zealand White Rabbit

Henriksson, Helena Barreto; Svala, Emilia; Skiöldebrand, Eva; Lindahl, Anders; Brisby, Helena

Sammanfattning

Conclusion. The results suggest a cellular MR from the IVD stem cell niche toward the annulus fibrosus and the inner parts of the IVD. These findings may be of importance for understanding IVD regenerative mechanisms and for future development of biological treatment strategies.

Nyckelord

disc regeneration; cell migration; stem cell niches; intervertebral disc; in vivo labeling; BrdU; GDF5

Publicerad i

Spine
2012, volym: 37, nummer: 9, sidor: 722-732
Utgivare: LIPPINCOTT WILLIAMS & WILKINS

SLU författare

Svala, Emilia
- Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
Skiöldebrand, Eva
- Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet

UKÄ forskningsämne

Neurovetenskaper

Publikationens identifierare

DOI: https://doi.org/10.1097/BRS.0b013e318231c2f7

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/45616