Research article - Peer-reviewed, 2011
Influence of Dietary Sesamin, a Bioactive Compound on Fatty Acids and Expression of Some Lipid Regulating Genes in Baltic Atlantic Salmon (Salmo salar L.) Juveniles
Trattner, S.; Ruyter, B.; Ostbye, T. K.; Kamal-Eldin, A.; Moazzami, A.; Pan, J.; Gjoen, T.; Brannas, E.; Zlabek, V.; Pickova, J.Abstract
The effects of inclusion of sesamin / episesamin in Baltic Atlantic salmon (Salmo salar L.) diets based on vegetable oils were studied. The study was designed as a dose response study with two control diets, one diet based on fish oil (FO) and one diet based on a mixture of linseed and sunflower oil (6:4 by vol.) (MO). As experimental diets three different levels of inclusion of sesamin / episesamin (hereafter named sesamin) to the MO based diet and one diet based on sesame oil and linseed oil (SesO) (1:1 by vol.) were used. The dietary oils were mirrored in the fatty acid profile of the white muscle. Sesamin significantly decreased the levels of 18:3n-3 in the white muscle phospholipid (PL) fraction of all groups fed sesamin, no significant differences were found in the triacylglycerol fraction (TAG). Slightly increased levels of docosahexaenoic acid (22:6n-3, DHA) in PL and TAG were found in some of the sesamin fed groups. Sesamin significantly affected the expression of peroxisome proliferator-activated receptor a, scavenger receptor type B and hormone sensitive lipase, in agreement with previous studies on rainbow trout (Oncorhynchus mykiss) and Atlantic salmon (Salmo salar L.) hepatocytes published by our group. No significant effects on toxicological response measured as ethoxyresorufin O-deethylase activity was found. The total cytochrome P450 enzymes were significantly higher in MO 0.29 and SesO group. The amount of alpha- and y-tocopherols in liver and the amount of.-tocopherol in white muscle were significantly lower in fish fed the FO diet compared to the MO diet, but no difference after inclusion of sesamin was found in this study. Increased inclusion of sesamin increased the levels of sesamin and episesamin in the liver, but did not affect the amounts in white muscle.Keywords
Sesamin; Episesamin; Tocopherols; Cytochrome P450; Peroxisome proliferator-activated receptor; Hormone sensitive lipase; Scavenger receptor type BPublished in
Physiological Research // Academia Scientiarum Bohemoslovaca2011, volume: 60, number: 1, pages: 125-137
Publisher: ACAD SCIENCES CZECH REPUBLIC, INST PHYSIOLOGY
Authors' information
Trattner, Sofia
Swedish University of Agricultural Sciences, Department of Food Science
Trattner, Sofia
Swedish University of Agricultural Sciences, Department of Wildlife, Fish and Environmental Studies
Ruyter, B
Nofima
Østbye, T. K.
Nofima
Kamal-Eldin, Afaf
Swedish University of Agricultural Sciences, Department of Food Science
Swedish University of Agricultural Sciences, Department of Food Science
Pan, Jinfeng
Swedish University of Agricultural Sciences, Department of Food Science
Gjøen, T.
University of Oslo (UiO)
Brännäs, Eva
Swedish University of Agricultural Sciences, Department of Wildlife, Fish and Environmental Studies
Zlabek, Vladimir
Swedish University of Agricultural Sciences, Department of Food Science
Zlabek, Vladimir
University of South Bohemia in České Budějovice
Swedish University of Agricultural Sciences, Department of Food Science
University of South Bohemia in České Budějovice
UKÄ Subject classification
Fish and Aquacultural Science
Environmental Sciences related to Agriculture and Land-use
URI (permanent link to this page)
https://res.slu.se/id/publ/47067