Plasma oxytocin changes and anti-obsessive response during serotonin reuptake inhibitor treatment: a placebo controlled study

Abstract

Conclusions: SRIs have highly variable effects on plasma oxytocin between individuals. The associations between baseline oxytocin and OCD severity and between oxytocin changes and treatment response support the notions that oxytocin is involved in OCD pathophysiology, and that the anti-obsessive effects of SRIs are partly exerted through oxytocinergic mechanisms.

Keywords

Obsessive-compulsive disorder; Oxytocin/plasma; Serotonin; Serotonin uptake inhibitors; Treatment response; Randomized controlled trial; Autism spectrum disorder; Placebo response

Published in

BMC Psychiatry
2013, volume: 13
Publisher: BIOMED CENTRAL LTD

SLU Authors

• Uvnäs-Moberg, Kerstin

  • Department of Applied Animal Science and Welfare, Swedish University of Agricultural Sciences
    

UKÄ Subject classification

Psychiatry

Publication identifier

• DOI: https://doi.org/10.1186/1471-244X-13-344

Permanent link to this page (URI)

https://res.slu.se/id/publ/55284