Immunohistochemical investigation into the distribution pattern of myoepithelial cells in the bovine mammary gland

Sammanfattning

The distribution pattern of myoepithelial cells in the bovine mammary gland was investigated by an immunohistochemical technique, using monoclonal antibodies against cytokeratins 5, 6 and 18 and cytokeratins 8 and 14 and against a-smooth-muscle actin filaments. Myoepithelial cells were shown to be present as a continuous basal cell layer in the intralobular ducts, as discontinuous cell rows in the basal cell layer of the interlobular ducts, and as single cells dispersed in the basal cell layer of the quarter cisterns, while they were apparently absent in the teat cisterns. Unlike the case with myoepithelial cells of the human breast, anticytokeratin 14 was less specific as a marker of bovine myoepithelial cells than was anti-cz-smooth-muscle actin.

Publicerad i

Journal of Dairy Research
1997, volym: 64, nummer: 2, sidor: 197-205
Utgivare: CAMBRIDGE UNIV PRESS

SLU författare

• Hellmén, Eva

  • Institutionen för patologi, Sveriges lantbruksuniversitet
    

UKÄ forskningsämne

Patobiologi

Publikationens identifierare

• DOI: https://doi.org/10.1017/S0022029997002148

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/64782