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Review article2014Peer reviewed

An update on alkylresorcinols - Occurrence, bioavailability, bioactivity and utility as biomarkers

Landberg, Rikard; Marklund, Matti; Kamal-Eldin, Afaf; Åman, Per

Abstract

Alkylresorcinols (AR) with alkyl chains in the range of C15 to C25 are phenolic lipids particularly abundant in the outer parts of wheat and rye kernels and in food products containing these parts. The content in whole grain and bran products is high (200-4000 mu g/g), whereas only trace-levels are detected in refined products. Alkylresorcinols are absorbed in humans in proportion to intake and have therefore been suggested and evaluated as biomarkers for whole grain wheat and rye intake. In humans, plasma AR concentrations reach micromolar concentrations immediately after whole grain wheat and rye product consumption and nano-molar levels at fasting conditions. Results from different model studies have indicated that AR may have some bioactivities including enzyme inhibition, suppression of adipocyte lipolysis and inhibition of colon cancer tumor growth but it is currently unknown whether AR bioactive in vivo or not. This chapter details the recent research findings on alkylresorcinols with emphasis on their occurrence, bioavailability, bioactivity and utility as biomarkers. (C) 2013 Elsevier Ltd. All rights reserved.

Keywords

Alkylresoricinols; Biomarkers; Bioavailability; Bioactivity

Published in

Journal of Functional Foods
2014, Volume: 7, pages: 77-89
Publisher: ELSEVIER SCIENCE BV

      SLU Authors

        • Sustainable Development Goals

        Ensure healthy lives and promote well-being for all at all ages
        End hunger, achieve food security and improved nutrition and promote sustainable agriculture

        UKÄ Subject classification

        Food Science

        Publication identifier

        DOI: https://doi.org/10.1016/j.jff.2013.09.004

        Permanent link to this page (URI)

        https://res.slu.se/id/publ/66669