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Forskningsartikel - Refereegranskat, 2015

Percutaneously inserted long-term central venous catheters in pigs of different sizes

Larsson N, Lingehall HC, Al Zaidi N, Claesson J, Jensen-Waern M, Lehtipalo S

Sammanfattning

Pigs are used for long-term biomedical experiments requiring repeated injections, infusions and collections of blood samples. Thus, it is necessary for vascular catheters to be indwelling to avoid undue stress to the animals and the use of restraints. We propose a refined model of percutaneous insertion of long-term central venous catheters to minimize the surgical trauma and postoperative complications associated with catheter insertion. Different sizes of needles (18 Ga versus 21 Ga) for initial puncture of the veins were compared. In conventional pigs weighing less than 30kg, catheter insertion may be facilitated by using a microintroducer set with a 21 Ga needle. In pigs weighing 50kg, a standard 18 Ga needle may be preferable.

Nyckelord

microintroducer; Seldinger technique; swine; vascular access; refinement

Publicerad i

Laboratory Animals
2015, Volym: 49, nummer: 3, sidor: 215-219