Forskningsartikel2013Vetenskapligt granskad
Periconceptional undernutrition in sheep leads to decreased locomotor activity in a natural environment
Donovan, E. L.; Hernandez, C. E.; Matthews, L. R.; Oliver, M. H.; Jaquiery, A. L.; Bloomfield, F. H.; Harding, J. E.
Sammanfattning
Maternal undernutrition during pregnancy increases offspring obesity and metabolic disease risk. We hypothesized that periconceptional undernutrition in sheep from 60 days before conception through to day 30 of gestation (UN) would decrease voluntary locomotor activity in adult offspring. Distance travelled was measured at 18 months of age for similar to 48 h in the paddock. Data were analysed using multiple regression analysis, with explanatory variables including sex, nutrition group, birth weight, average time between GPS measurements and percentage of time during the measurement period spent in daylight. Mean (+/- S.E.) distance walked (m/h) was greater for control (CON) than UN animals, and greater for females than males [110.2 (6.5), CON females; 110.7 (6.3), CON males; 105.1 (5.3), UN females and 95.5 (5.8), UN males; P=0.02 for nutrition group effect and for sex effect]. Periconceptional undernutrition may lead to a significant decrease in voluntary physical activity in adult offspring.
Nyckelord
developmental programming; obesity; physical activity; undernutrition
Publicerad i
Journal of Developmental Origins of Health and Disease
2013, Volym: 4, nummer: 4, sidor: 296-299
UKÄ forskningsämne
Husdjursvetenskap
Publikationens identifierare
DOI: https://doi.org/10.1017/S2040174413000214
Permanent länk till denna sida (URI)
https://res.slu.se/id/publ/86391