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Översiktsartikel - Refereegranskat, 2014

Interactions of Xanthomonas type-III effector proteins with the plant ubiquitin and ubiquitin-like pathways

Uestuen, Suayib; Boernke, Frederik

Sammanfattning

In eukaryotes, regulated protein turnover is required during many cellular processes, including defense against pathogens. Ubiquitination and degradation of ubiquitinated proteins via the ubiquitin proteasome system (UPS) is the main pathway for the turnover of intracellular proteins in eukaryotes. The extensive utilization of the UPS in host cells makes it an ideal pivot for the manipulation of cellular processes by pathogens. Like many other Gram-negative bacteria, Xanthomonas species secrete a suite of type-III effector proteins (T3Es) into their host cells to promote virulence. Some of these T3Es exploit the plant UPS to interfere with immunity. This review summarizes T3E examples from the genus Xanthomonas with a proven or suggested interaction with the host UPS or UPS-like systems and also discusses the apparent paradox that arises from the presence of T3Es that inhibit the UPS in general while others rely on its activity for their function.

Nyckelord

Xanthomonas; type-III effector; ubiquitin; proteasome; plant defense

Publicerad i

Frontiers in Plant Science
2014, Volym: 5, artikelnummer: 736
Utgivare: FRONTIERS RESEARCH FOUNDATION

    UKÄ forskningsämne

    Biochemistry and Molecular Biology

    Publikationens identifierare

    DOI: https://doi.org/10.3389/fpls.2014.00736

    Permanent länk till denna sida (URI)

    https://res.slu.se/id/publ/87541