A family of putative transcription termination factors shared amongst metazoans and plants

Sammanfattning

The human mitochondrial transcription termination factor (mTERF) is involved in the regulation of transcription of the mitochondrial genome. Similarity searches and phylogenetic analysis demonstrate that mTERF is a member of large and complex protein family (the MTERF family) shared amongst metazoans and plants. Interestingly, we identify three novel MTERF genes in vertebrates, which all encode proteins with predicted mitochondrial localization. Members of the MTERF family have so far not been detected in fungi, supporting the notion that mitochondrial transcription regulation may have evolved separately in yeast and animal cells.

Nyckelord

mTERF; transcription; mitochondrion; termination

Publicerad i

Current Genetics
2005, volym: 48, nummer: 4, sidor: 265-269
Utgivare: SPRINGER

SLU författare

• Linder, Tomas

  • Karolinska institutet

UKÄ forskningsämne

Bioinformatik och beräkningsbiologi (Metodutveckling under 10203)

Publikationens identifierare

• DOI: https://doi.org/10.1007/s00294-005-0022-5

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/90880