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Forskningsartikel2005Vetenskapligt granskad

A family of putative transcription termination factors shared amongst metazoans and plants

Linder, T; Park, CB; Asin-Cayuela, J; Pellegrini, M; Larsson, NG; Falkenberg, M; Samuelsson, T; Gustafsson, CM

Sammanfattning

The human mitochondrial transcription termination factor (mTERF) is involved in the regulation of transcription of the mitochondrial genome. Similarity searches and phylogenetic analysis demonstrate that mTERF is a member of large and complex protein family (the MTERF family) shared amongst metazoans and plants. Interestingly, we identify three novel MTERF genes in vertebrates, which all encode proteins with predicted mitochondrial localization. Members of the MTERF family have so far not been detected in fungi, supporting the notion that mitochondrial transcription regulation may have evolved separately in yeast and animal cells.

Nyckelord

mTERF; transcription; mitochondrion; termination

Publicerad i

Current Genetics
2005, Volym: 48, nummer: 4, sidor: 265-269 Utgivare: SPRINGER

    UKÄ forskningsämne

    Bioinformatik och systembiologi

    Publikationens identifierare

    DOI: https://doi.org/10.1007/s00294-005-0022-5

    Permanent länk till denna sida (URI)

    https://res.slu.se/id/publ/90880