- Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences
Landreh, Michael; Andersson, Marlene; Marklund, Erik G.; Jia, Qiupin; Meng, Qing; Johansson, Jan; Robinson, Carol V.; Rising, Anna
Self-assembling proteins, the basis for a broad range of biological scaffolds, are challenging to study using most structural biology approaches. Here we show that mass spectrometry (MS) in combination with MD simulations captures structural features of short-lived oligomeric intermediates in spider silk formation, providing direct insights into its complex assembly process.
2017, Volume: 53, number: 23, pages: 3319-3322
Publisher: ROYAL SOC CHEMISTRY
Biochemistry and Molecular Biology