Correspondence on Lovell et al.: identification of chicken genes previously assumed to be evolutionarily lost

Bornelov, Susanne; Seroussi, Eyal; Yosefi, Sara; Pendavis, Ken; Burgess, Shane C.; Grabherr, Manfred; Friedman-Einat, Miriam; Andersson, Leif

doi:10.1186/s13059-017-1231-1

Forskningsartikel2017Vetenskapligt granskadÖppen tillgång

Correspondence on Lovell et al.: identification of chicken genes previously assumed to be evolutionarily lost

Bornelov, Susanne; Seroussi, Eyal; Yosefi, Sara; Pendavis, Ken; Burgess, Shane C.; Grabherr, Manfred; Friedman-Einat, Miriam; Andersson, Leif

Sammanfattning

Through RNA-Seq analyses, we identified 137 genes that are missing in chicken, including the long-sought-after nephrin and tumor necrosis factor genes. These genes tended to cluster in GC-rich regions that have poor coverage in genome sequence databases. Hence, the occurrence of syntenic groups of vertebrate genes that have not been observed in Aves does not prove the evolutionary loss of such genes.

Publicerad i

Genome Biology
2017, Volym: 18, artikelnummer: 112
Utgivare: BIOMED CENTRAL LTD

SLU författare

Andersson, Leif
- Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
- Texas A&M University
- Uppsala universitet

UKÄ forskningsämne

Genetik och förädling

Publikationens identifierare

DOI: https://doi.org/10.1186/s13059-017-1231-1

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/91110