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Research article2018Peer reviewedOpen access

Safety of low-substituted hydroxypropyl cellulose (L-HPC) to be used as a food additive in food supplements in tablet form

Younes, Maged; Aggett, Peter; Aguilar, Fernando; Crebelli, Riccardo; Dusemund, Birgit; Filipic, Metka; Frutos, Maria Jose; Galtier, Pierre; Gundert-Remy, Ursula; Kuhnle, Gunter Georg; Lambre, Claude; Leblanc, Jean-Charles; Lillegaard, Inger Therese; Moldeus, Peter; Mortensen, Alicja; Oskarsson, Agneta; Stankovic, Ivan; Waalkens-Berendsen, Ine; Woutersen, Rudolf Antonius; Wright, Matthew;
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Abstract

Low-substituted hydroxypropyl cellulose (L-HPC) is a low-substituted poly(hydroxypropyl) ether of cellulose. L-HPC is proposed for use as a food additive in food supplements in solid form (tablet), with a maximum use level of 20,000 mg/kg and a typical use level of 10,000 mg/kg. Exposure estimates to L-HPC from its proposed use were calculated for both typical and maximum use levels. Due to the close chemical relationship between L-HPC and other celluloses recently re-evaluated by EFSA, the Paneldecided to read-across the biological data already evaluated in the context of the re-evaluation programme. The Panelconcluded that there was no safety concern from the proposed use and use levels of L-HPC. (C) 2018 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority.

Keywords

food additive; low-substituted hydroxypropyl cellulose; L-HPC; food supplements

Published in

EFSA Journal
2018, Volume: 16, number: 1, article number: 5062

    UKÄ Subject classification

    Public Health, Global Health, Social Medicine and Epidemiology

    Publication identifier

    DOI: https://doi.org/10.2903/j.efsa.2018.5062

    Permanent link to this page (URI)

    https://res.slu.se/id/publ/96757