Cellular and humoral immune alterations during the clinical and recovery phases of experimental swine dysentery

Abstract

Pigs were inoculated with B.hyodysenteriae. Blood was sampled before inoculation, at clinical signs of swine dysentery and during 3 weeks of recovery. Dysentery pigs had elevated levels of Serum Amyloid A and circulating neutrophils, monocytes, CD8+ cells and activated (CD45RA) lymphocytes during dysentery. The CD8+ cells where mainly CD4and CD8. There was a decrease in B cells and an increase in  T cells after inoculation. Serum antibodies where present at day 7 of the recovery from clinical symptoms and onwards. The alterations in protein metabolism and its role will also be addressed

SLU Authors

• Kruse, Robert

  • Department of Clinical Sciences, Swedish University of Agricultural Sciences
    

• Andersson, Märit

  • Department of Clinical Sciences, Swedish University of Agricultural Sciences
    

• Råsbäck, Therese

  • Department of Clinical Sciences, Swedish University of Agricultural Sciences
    

• Johannisson, Anders

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

• Fellström, Claes

  • Department of Clinical Sciences, Swedish University of Agricultural Sciences
    

• Jensen Waern, Marianne

  • Department of Clinical Sciences, Swedish University of Agricultural Sciences
    

UKÄ Subject classification

Veterinary Science
Animal and Dairy Science

Permanent link to this page (URI)

https://res.slu.se/id/publ/9600