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Sammanfattning

Oxytocin induces a tong-lasting reduction of blood pressure in rats. The aim of the present study was to investigate the effects of an acute stressor on blood pressure and heart rate in rats previously exposed to repeated administration of intracerebroventricular (ICV) oxytocin. For this purpose oxytocin (0.3 mu g, ICV) was administered to mate rats once a day during 5 days. Blood pressure and heart rate were measured before and after treatment. In addition, blood pressure and heart rate were measured during 30 min after exposure to 10s of noise from an alarm clock.The oxytocin treatment reduced blood pressure significantly (systolic: 108+/-4.6 vs. 121 +/-1.8, p

Nyckelord

oxytocin; rat; blood pressure; heart rate; stress

Publicerad i

Psychoneuroendocrinology
2007, volym: 32, nummer: 8-10, sidor: 959-965

SLU författare

UKÄ forskningsämne

Zoologi

Publikationens identifierare

  • DOI: https://doi.org/10.1016/j.psyneuen.2007.06.015

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/104468