Reproduction of postweaning multisystemic wasting syndrome in pigs experimentally inoculated with a Swedish porcine circovirus 2 isolate

Sammanfattning

In recent years, porcine circovirus type 2 (PCV2)-associated postweaning multisystemic wasting syndrome (PMWS) has been reported worldwide. However, to date, PMWS has not been reported in Sweden despite the demonstration of serum antibodies to a PCV2-like virus in Swedish pigs. This communication reports the experimental reproduction of clinical PMWS after inoculation of colostrum-deprived (CD) pigs, derived from a Northern Ireland herd, with an isolate of PCV2 virus recovered from a clinically normal Swedish pig that was necropsied in 1993. The clinical disease and histological lesions observed in CD pigs inoculated with this virus were indistinguishable from those observed in previous studies on CD pigs inoculated with a PCV2 virus isolate recovered from pigs with PMWS. These results highlight the disease potential of PCV2 isolated from regions apparently free of PMWS and suggest that the status of the host and its environment is an important factor in the development of clinical PMWS

Publicerad i

Journal of Veterinary Diagnostic Investigation
2003, volym: 15, nummer: 6, sidor: 553-560
Utgivare: AMER ASSOC VETERINARY LABORATORY DIAGNOSTICIANS INC

SLU författare

• Wattrang, Eva

  • Institutionen för molekylär biovetenskap, Sveriges lantbruksuniversitet
    

• Fossum, Caroline

  • Institutionen för molekylär biovetenskap, Sveriges lantbruksuniversitet
    

UKÄ forskningsämne

Annan veterinärmedicin

Publikationens identifierare

• DOI: https://doi.org/10.1177/104063870301500607

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/1054