Evaluation of alkylresorcinols in adipose tissue biopsies as a long-term biomarker of whole-grain wheat and rye intake in free-living Swedish men and women

Sammanfattning

Objective: Wheat and rye, the most consumed whole grains (WG) in the Nordic countries, contain alkylresorcinols (AR) in their bran. AR concentrations in human adipose tissue might reflect long-term WG rye and wheat intake. We aimed to evaluate AR concentrations in adipose tissue biopsies as a long-term biomarker of WG wheat and rye intake in free-living Swedish men and women.Design: Cross-sectional study. AR concentrations in adipose tissue biopsies were analysed and compared with long-term WG intake assessed by three FFQ (repeated over a period of 14 years in men, 17 years in women) and with plasma AR concentrations.Setting: The Cohort of Swedish Men between 1997 and 2010 and the Swedish Mammography Cohort between 1987 and 2003, Sweden.Subjects: Men (n 149) and women (n 109).Results: Long-term WG rye intake estimated with repeated FFQ correlated (r = 0.31-0.41, P

Nyckelord

Dietary biomarker; Alkylresordnol; Whole grain; Adipose tissue; Plasma

Publicerad i

Public Health Nutrition
2018, volym: 21, nummer: 10, sidor: 1933-1942
Utgivare: CAMBRIDGE UNIV PRESS

SLU författare

• Wu, Huaxing

  • Institutionen för molekylära vetenskaper, Sveriges lantbruksuniversitet
    

• Landberg, Rikard

  • Institutionen för molekylära vetenskaper, Sveriges lantbruksuniversitet
    
  • Chalmers Tekniska Högskola
  • Karolinska institutet

Globala målen (SDG)

SDG3 God hälsa och välbefinnande

UKÄ forskningsämne

Näringslära och dietkunskap

Publikationens identifierare

• DOI: https://doi.org/10.1017/S1368980018000484

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/97563