Yi, Jun
- Institutionen för växtbiologi, Sveriges lantbruksuniversitet
Forskningsartikel2015Vetenskapligt granskadÖppen tillgång
Brownfield, Lynette; Yi, Jun; Jiang, Hua; Minina, Alyona; Twell, David; Köhler, Claudia
Accurate positioning of spindles is a critical aspect of cell division as it ensures that each daughter cell contains a single nucleus. In many flowering plants, two meiotic chromosome separations occur without intervening cytokinesis, resulting in two spindles in one cell during the second division. Here we report a detailed examination of two mutants, jason (jas) and parallel spindle1 (ps1), in which disturbed spindle position during male meiosis II results in the incorporation of previously separated chromosome groups into a single cell. Our study reveals that an organelle band provides a physical barrier between the two spindles. The loss of a single protein, JAS, from this organelle band leads to its disruption and a random movement of the spindles. JAS is largely associated with vesicles in the organelle band, revealing a role for vesicles in plant meiosis and that cytoplasmic events maintain spindle position during the chromosome division.
Nature Communications
2015, Volym: 6, artikelnummer: 6492
Utgivare: NATURE PUBLISHING GROUP
Genetik
Cellbiologi
DOI: https://doi.org/10.1038/ncomms7492
https://res.slu.se/id/publ/72362