Gene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies

Sammanfattning

Conclusions: Early IVD degeneration involves down-regulation of canonical Wnt signaling and Caveolin-1 expression, which appears to be essential to the physiology and preservation of NCs. Therefore, Caveolin-1 may be regarded an exciting target for developing strategies for IVD regeneration.

Publicerad i

Arthritis Research and Therapy
2013, volym: 15, nummer: 1
Utgivare: BIOMED CENTRAL LTD

SLU författare

• Bergknut, Niklas

  • Institutionen för kliniska vetenskaper, Sveriges lantbruksuniversitet
    

UKÄ forskningsämne

Annan veterinärmedicin

Publikationens identifierare

• DOI: https://doi.org/10.1186/ar4157

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/50356