Salmon Hillbertz, Nicolette
- Institutionen för husdjursgenetik, Sveriges lantbruksuniversitet
Hillbertz NHCS, Isaksson M, Karlsson EK, Hellmen E, Pielberg GR, Savolainen P, Wade CM, Von Euler H, Gustafson U, Hedhammar K, Nilsson M, Lindblad-Toh K, Andersson L, Andersson G
The dorsal hair ridge in Rhodesian and Thai Ridgeback dogs is caused by a dominant mutation that also predisposes to the congenital developmental disorder dermoid sinus. Here we show that the causative mutation is a 133-kb duplication involving three fibroblast growth factor (FGF) genes. FGFs play a crucial role in development, suggesting that the ridge and dermoid sinus are caused by dysregulation of one or more of the three FGF genes during development
Nature Genetics
2007, Volym: 39, nummer: 11, sidor: 1318-1320
Utgivare: NATURE PUBLISHING GROUP
Veterinary Science
Animal and Dairy Science
https://res.slu.se/id/publ/16369