Salmon Hillbertz, Nicolette
- Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
Forskningsartikel2007Vetenskapligt granskad
Hillbertz NHCS, Isaksson M, Karlsson EK, Hellmen E, Pielberg GR, Savolainen P, Wade CM, Von Euler H, Gustafson U, Hedhammar K, Nilsson M, Lindblad-Toh K, Andersson L, Andersson G
The dorsal hair ridge in Rhodesian and Thai Ridgeback dogs is caused by a dominant mutation that also predisposes to the congenital developmental disorder dermoid sinus. Here we show that the causative mutation is a 133-kb duplication involving three fibroblast growth factor (FGF) genes. FGFs play a crucial role in development, suggesting that the ridge and dermoid sinus are caused by dysregulation of one or more of the three FGF genes during development
Nature Genetics
2007, Volym: 39, nummer: 11, sidor: 1318-1320 Utgivare: NATURE PUBLISHING GROUP
Veterinärmedicin
Husdjursvetenskap
https://res.slu.se/id/publ/16369