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Sammanfattning

With several hundred genetic diseases and an advantageous genome structure, dogs are ideal for mapping genes that cause disease. Here we report the development of a genotyping array with similar to 27,000 SNPs and show that genome-wide association mapping of mendelian traits in dog breeds can be achieved with only similar to 20 dogs. Specifically, we map two traits with mendelian inheritance: the major white spotting ( S) locus and the hair ridge in Rhodesian ridgebacks. For both traits, we map the loci to discrete regions of

Publicerad i

Nature Genetics
2007, volym: 39, nummer: 11, sidor: 1321-1328
Utgivare: NATURE PUBLISHING GROUP

SLU författare

UKÄ forskningsämne

Veterinärmedicin
Husdjursvetenskap

Publikationens identifierare

  • DOI: https://doi.org/10.1038/ng.2007.10

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/16370