Wehelie, Rahma
- Department of Molecular Biosciences, Swedish University of Agricultural Sciences
Research article - Peer-reviewed, 2004
Effect of fluoropyrimidines on the growth of Ureaplasma urealyticum
Wehelie, Rahma; Eriksson, Staffan; Wang, Liya
Abstract
In the present study, we investigated the effect of fluoropyrimidines on the growth of Ureaplasma urealyticum. Addition of fluoropyrimidines strongly inhibited bacterial growth. Growth inhibition by these analogues could be reversed by addition of either thymidine or deoxyuridine, suggesting inhibition of thymidylate biosynthesis as the mechanism in operation.
Keywords
Ureaplasma; nucleoside analogues; growth inhibition; fluoropyrimidines
Published in
Nucleosides, Nucleotides and Nucleic Acids
2004, Volume: 23, number: 8-9, pages: 1499-1502
Eriksson, Staffan
- Department of Molecular Biosciences, Swedish University of Agricultural Sciences
- Department of Molecular Biosciences, Swedish University of Agricultural Sciences
Wang, Liya
- Department of Molecular Biosciences, Swedish University of Agricultural Sciences
- Department of Molecular Biosciences, Swedish University of Agricultural Sciences
SLU Authors
UKÄ Subject classification
Microbiology in the medical area
Publication Identifiers
DOI: https://doi.org/10.1081/NCN-200027714
Permanent link to this page (URI)
https://res.slu.se/id/publ/53110